Interleukin-12 Receptor 1 Deficiency Predisposing to Disseminated Coccidioidomycosis
نویسندگان
چکیده
منابع مشابه
Disseminated Coccidioidomycosis
Disseminated Coccidioidomycosis To the Editor: Coccidioidomy-cosis, an infection caused by the dimorphic fungus Coccidioides immi-tis, is endemic in the southwestern United States, parts of Mexico, and Central and South America (1). Patients with C. immitis infection may have chronic pneumonia, fungemia, and extrapulmonary dissemination to skin, bones, meninges, and other body sites. The clinic...
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We describe a child with interleukin-12 receptor beta1 (IL-12Rbeta1) deficiency caused by a homozygous IL12RB1 large deletion who presented at the age of 1 year with recurrent, often asymptomatic episodes of bacteremia caused by group D Salmonella species. No mycobacterial disease or other unusual infection was present. The episodes of salmonellosis were caused by an identical serovar during a ...
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In Europe most authors consider that histoplasmosis due to Histoplasma capsulatum is a rare imported fungal disease that is only diagnosed when it appears in the disseminated form. Such a presentation is very unusual in areas where it is endemic.' This paradox is explicable because in most cases infection is localised, so that in endemic areas cases of dissemination represent a very small propo...
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INTRODUCTION Interleukin 12 receptor beta 1 (IL12Rβ1) deficiency is a primary immunodeficiency resulting mainly in susceptibility to opportunistic infection by non-tuberculous, environmental mycobacteria and severe infection caused by Salmonella spp. Till now, less than 300 patients with IL12Rβ1 deficiency have been reported. Among them, only three have been described to develop autoimmunity. ...
متن کاملSarcoidosis possibly predisposing to disseminated histoplasmosis.
In Europe most authors consider that histoplasmosis due to Histoplasma capsulatum is a rare imported fungal disease that is only diagnosed when it appears in the disseminated form. Such a presentation is very unusual in areas where it is endemic.' This paradox is explicable because in most cases infection is localised, so that in endemic areas cases of dissemination represent a very small propo...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2011
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciq215